pentobarbital will reduce the extent or influence of ethotoin by impacting hepatic enzyme CYP2C9/10 metabolism. Use Caution/Check.
pentobarbital will lessen the extent or impact of itraconazole by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Insignificant/Importance Unfamiliar.
pentobarbital will reduce the extent or impact of lorlatinib by influencing hepatic/intestinal enzyme CYP3A4 metabolism.
pentobarbital will decrease the level or impact of alprazolam by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Observe.
Keep an eye on Intently (one)pentobarbital will minimize the extent or impact of osilodrostat by impacting hepatic/intestinal enzyme CYP3A4 metabolism.
Watch Closely (one)pentobarbital will lessen the level or impact of mifepristone by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Watch. CYP3A4 inducers haven't been studied, coadministration not advisable by company
pentobarbital will lower the level or outcome of estrogens conjugated synthetic by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Observe.
pentobarbital will lessen the extent or impact of ramelteon by impacting hepatic enzyme CYP2C9/10 metabolism. Insignificant/Importance Unfamiliar.
pentobarbital will minimize the extent or effect of ritonavir by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Check.
pentobarbital will lower the level or outcome of doravirine by influencing hepatic/intestinal enzyme CYP3A4 metabolism.
Observe Intently (one)pentobarbital will lower the extent or impact of hydrocodone by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Check Carefully. Warning when discontinuing CYP3A4 inducers which read more might be coadministered with hydrocodone; plasma concentrations of hydrocodone may well maximize and may result in possibly lethal respiratory depressionSerious - Use Choice (1)hydrocodone, pentobarbital.
Monitor Intently (3)pentobarbital will decrease the level or outcome of diazepam intranasal by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Check. Powerful or reasonable CYP3A4 inducers could raise level of diazepam elimination; consequently, efficacy of diazepam may very well be decreased.
pentobarbital will decrease the extent or influence of fedratinib by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Keep away from or Use Alternate Drug. Result of coadministering a strong CYP3A4 inducer with fedratinib hasn't been researched.
Check Closely (two)pentobarbital will lessen the level or outcome of oliceridine by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor. If coadministration with a CYP3A4 inducer is essential, look at escalating oliceridine dose until eventually stable drug effects are realized; keep track of for signs of opioid withdrawal.